I nā makahiki i hala iho nei, ʻo ka ʻenehana nano-drug kahi ʻenehana hou kaulana i ka ʻenehana hoʻomākaukau lāʻau.Nano lāʻau lapaʻau e like me nanoparticles, poepoe a nano capsule nanoparticles e like me ka mea lawe nenoaiu, a me ka efficacy o na particles i kekahi ala pu ma hope o ka lāʻau lapaʻau, hiki no hoi ke hana pololei i ka oaoieei hana o nanoparticles.
Ke hoʻohālikelike ʻia me nā lāʻau lapaʻau maʻamau, he nui nā pono o nā nano-drugs i hiki ʻole ke hoʻohālikelike ʻia me nā lāʻau lapaʻau maʻamau:
He lāʻau hoʻokuʻu lohi, hoʻololi i ka hapalua o ke ola o ka lāʻau i loko o ke kino, e hoʻolōʻihi i ka manawa hana o ka lāʻau;
Hiki ke kiʻi ʻia kahi ʻōkana pahuhopu ma hope o ka hana ʻia ʻana i lāʻau alakaʻi;
No ka hōʻemi ʻana i ka dosage, hōʻemi a hoʻopau paha i ka hopena ʻona ma lalo o ka manaʻo o ka hōʻoia ʻana i ka pono;
Hoʻololi ʻia ka mīkini transport membrane e hoʻonui i ka permeability o ka lāʻau i ka biofilm, kahi mea e pono ai i ka lāʻau transdermal absorption a me ka pāʻani o ka lāʻau efficacy.
No laila no kēlā mau mea e pono ai me ke kōkua o kahi mea lawe e hāʻawi i nā lāʻau lapaʻau i nā pahuhopu kikoʻī, e hāʻawi i ka pāʻani i ke kuleana o ka mālama ʻana ma ke ʻano o nā nanodrugs, ʻo ka hoʻolālā ʻana o ka mea lawe e hoʻomaikaʻi i ka pono o ka huli ʻana i ka lāʻau.
ʻO ka nūhou hou i ʻōlelo ʻia e ke kulanui o New South Wales, Australia, ua hoʻomohala nā mea noiʻi i kahi ala hou, hiki ke hoʻololi i ke ʻano o ka mea lawe lāʻau nano nano, e kōkua kēia i ka lawe ʻana i nā lāʻau anti-cancer i hoʻokuʻu ʻia i loko o ka ʻōpū, hoʻomaikaʻi i ka hopena o ka anti-cancer. - nā lāʻau maʻi kanesa.
Hiki ke hoʻokumu ʻia nā molekala Polymer i ka hopena vesicles hollow spherical structure o ka polymer, loaʻa iā ia nā pōmaikaʻi o ka paʻa ikaika, hoʻohana nui ʻia ka ʻokoʻa hana e like me ka mea lawe lāʻau, akā, ma ka ʻokoʻa, e like me ka bacteria a me ka maʻi virus i ke ʻano he mau paipu, koʻokoʻo. , a hiki ke maʻalahi ke komo ʻana i ke kino o nā mea ola kino ʻole.Ma muli o ka paʻakikī o ka polymer vesicle e hana i kahi ʻano nonspherical, ua kaupalena kēia i ka hiki o ka polymer ke hoʻopuka i nā lāʻau lapaʻau i kona wahi i loko o ke kino o ke kanaka i kekahi ʻano.
Ua hoʻohana nā mea noiʻi o Australia i ka microscopy cryoelectron e nānā i nā hoʻololi ʻana o nā molekele polymer i ka hopena.Ua ʻike lākou ma ka hoʻololi ʻana i ka nui o ka wai i ka solvent, hiki ke hoʻoponopono ʻia ke ʻano a me ka nui o nā vesicle polymer ma o ka hoʻololi ʻana i ka nui o ka wai i ka solvent.
Ua ʻōlelo ʻo ka mea kākau alakaʻi a me ke kulanui o New South Wales institute of chemistry of pine parr sol: "ʻO kēia ka hopena hiki iā mākou ke hana i ka polymer vesicle shape hiki ke loli me ke kaiapuni, e like me ka oval a i ʻole tubular, a me ka pūʻolo lāʻau i loko."Hōʻike nā hōʻike mua i ka mea ʻoi aku ka nui o nā mea lawe nano-lāʻau lāʻau kūlohelohe, ʻaʻole spherical e komo i loko o nā pūnana tumora.
Ua paʻi ʻia ka noiʻi ma ka pūnaewele ma ka pukana hou loa o ka puke pai nature communications.
Ka manawa hoʻouna: Jul-04-2022