Ua kūkulu nā kānaka ʻepekema i kahua no ka hoʻohui ʻana i nā ʻāpana mea nanosized, a i ʻole "nā mea-nano," o nā ʻano ʻokoʻa loa - inorganic a i ʻole organik - i loko o nā hale 3-D i makemake ʻia. ʻOiai ua hoʻohana maikaʻi ʻia ʻo self-assembly (SA) no ka hoʻonohonoho ʻana i nā nanomaterials o nā ʻano like ʻole, ʻo ke kaʻina hana he ʻōnaehana kikoʻī loa, e hana ana i nā hale like ʻole e pili ana i nā waiwai intrinsic o nā mea. E like me ka mea i hōʻike ʻia ma kahi pepa i paʻi ʻia i kēia lā ma Nature Materials, hiki ke hoʻohana ʻia kā lākou DNA-programmable nanofabrication platform e hoʻonohonoho i nā ʻano mea like ʻole 3-D i nā ala like i kuhikuhi ʻia ma ka nanoscale (billionths o ka mika), kahi o ka optical optical, chemical. , a puka mai na waiwai e ae.
"ʻO kekahi o nā kumu nui ʻaʻole ʻo SA he ʻano koho no nā noi kūpono ʻo ia ʻaʻole hiki ke hoʻohana ʻia ke kaʻina SA like ma waena o kahi ākea ākea o nā mea e hana ai i nā papa kuhikuhi 3-D like ʻole mai nā nanokompone like ʻole," i wehewehe ʻia ka mea kākau like ʻo Oleg Gang. , alakaʻi o ka Soft and Bio Nanomaterials Group ma ka Center for Functional Nanomaterials (CFN) - he US Department of Energy (DOE) Office of Science User Facility ma Brookhaven National Laboratory - a he polopeka. ʻO ka ʻenekinia Kemika a me ka ʻepekema noiʻi a me nā mea ʻepekema ma Columbia Engineering. "Eia, ua hoʻokaʻawale mākou i ke kaʻina SA mai nā waiwai waiwai ma o ka hoʻolālā ʻana i nā papa DNA polyhedral paʻa i hiki ke hoʻopili i nā ʻano nano-mea inorganic a i ʻole organik, me nā metala, semiconductors, a me nā protein a me nā enzymes."
Ua hana nā kānaka ʻepekema i nā kiʻi DNA synthetic i ke ʻano o ka cube, octahedron, a me tetrahedron. Aia i loko o nā kiʻi nā "lima" DNA e hiki ke hoʻopaʻa ʻia i nā mea nano wale nō me ke kaʻina DNA hoʻohui. ʻO kēia mau mea voxels - ka hoʻohui ʻana o ke kiʻi DNA a me ka nano-object - ʻo ia nā poloka kūkulu hale kahi e hiki ai ke hana i nā hale macroscale 3-D. Hoʻopili nā papa i kekahi i kekahi me ka nānā ʻole i ke ʻano o ka nano-mea i loko (a ʻaʻole paha) e like me nā kaʻina hoʻohui i hoʻopaʻa ʻia me ko lākou vertices. Ma muli o ko lākou ʻano, ʻokoʻa ka helu o nā vertice a no laila e hana ʻia nā hale ʻokoʻa. ʻO kēlā me kēia nano-mea i hoʻokipa ʻia i loko o nā kiʻi e lawe i kēlā ʻano hana kiʻi kikoʻī.
No ka hōʻike ʻana i kā lākou hui ʻana, ua koho nā ʻepekema i nā nanoparticles metallic (gula) a me semiconducting (cadmium selenide) a me kahi protein bacterial (streptavidin) ma ke ʻano he mea nano-anorganic a me ka organik e waiho ʻia i loko o nā pā DNA. ʻO ka mea mua, ua hōʻoia lākou i ka pono o nā papa DNA a me ka hoʻokumu ʻana i nā voxels waiwai ma ke kiʻi ʻana me nā microscopes electron ma ka CFN Electron Microscopy Facility a me ka Van Andel Institute, nona kahi hui o nā mea kani e hana ana i nā mahana cryogenic no nā laʻana olaola. A laila hoʻāʻo lākou i nā hale 3-D lattice ma ka Coherent Hard X-ray Scattering and Complex Materials Scattering beamlines o ka National Synchrotron Light Source II (NSLS-II) - kahi DOE Office of Science User Facility ma Brookhaven Lab. Ua hana ʻo Columbia Engineering Bykhovsky Professor of Chemical Engineering Sanat Kumar a me kāna pūʻulu i ka hoʻohālike hoʻohālikelike e hōʻike ana i ka hoʻokolohua ʻana i nā hale lattice i nānā ʻia (ma muli o nā kumu hoʻopuehu x-ray) ʻo ia nā mea paʻa thermodynamically i hiki i nā voxels waiwai ke hana.
"ʻO kēia mau mea voxels e ʻae iā mākou e hoʻomaka e hoʻohana i nā manaʻo i loaʻa mai nā ʻātoma (a me nā mole) a me nā kristal a lākou e hana ai, a e hoʻopili i kēia ʻike nui a me ka waihona i nā ʻōnaehana hoihoi ma ka nanoscale," wehewehe ʻo Kumar.
Ua hōʻike ʻia nā haumāna o Gang ma Columbia pehea e hoʻohana ʻia ai ke kahua hui e hoʻokele i ka hui ʻana o ʻelua mau ʻano mea like ʻole me nā hana kemika a me ka optical. I kekahi hihia, ua hui pū lākou i ʻelua enzymes, e hana ana i nā arrays 3-D me kahi kiʻekiʻe packing density. ʻOiai ʻaʻole i hoʻololi ʻia nā enzymes, ua hōʻike lākou i kahi piʻi ʻehā o ka hana enzymatic. Hiki ke hoʻohana ʻia kēia mau "nanoreactors" no ka hoʻoponopono ʻana i nā hopena cascade a hiki ke hana i nā mea hana kemika. No ka hōʻikeʻike mea optical, ua hui pū lākou i ʻelua kala like ʻole o nā kiko quantum - nā nanocrystals liʻiliʻi i hoʻohana ʻia e hana i nā hōʻike kīwī me ka saturation kala kiʻekiʻe a me ka ʻōlinolino. Ua hōʻike ʻia nā kiʻi i kiʻi ʻia me kahi microscope fluorescence i ka lattice i hana ʻia e mālama i ka maʻemaʻe kala ma lalo o ka palena diffraction (lōʻihi nalu) o ka mālamalama; hiki i kēia waiwai ke ʻae i ka hoʻomaikaʻi ʻana i ka hoʻonā koʻikoʻi i nā ʻano ʻike like ʻole a me nā ʻenehana kamaʻilio optical.
"Pono mākou e noʻonoʻo hou pehea e hana ʻia ai nā mea hana a pehea lākou e hana ai," wahi a Gang. “ʻAʻole pono paha ka hoʻolālā hou ʻana o nā mea; ʻO ka hoʻopili wale ʻana i nā mea i loaʻa i nā ala hou hiki ke hoʻonui i kā lākou waiwai. Hiki paha, hiki i kā mākou paepae ke lilo i ʻenehana hiki 'ma mua o ka hana paʻi 3-D' e hoʻomalu i nā mea ma nā unahi liʻiliʻi a me nā ʻano mea like ʻole a me nā haku mele. ʻO ka hoʻohana ʻana i ke ala like e hana ai i nā lattices 3-D mai nā mea nano i makemake ʻia o nā papa waiwai like ʻole, me ka hoʻohui ʻana i nā mea i manaʻo ʻia ʻaʻole kūpono, hiki ke hoʻololi i ka nanomanufacturing.
Nā mea i hāʻawi ʻia e DOE/Brookhaven National Laboratory. Nānā: Hiki ke hoʻoponopono ʻia ka ʻike no ke ʻano a me ka lōʻihi.
E kiʻi i ka nūhou ʻepekema hou loa me nā leka uila manuahi a ScienceDaily, i hoʻonui ʻia i kēlā me kēia lā a me kēlā me kēia pule. A i ʻole e nānā i nā nūhou hou i kēlā me kēia hola ma kāu mea heluhelu RSS:
E haʻi mai iā mākou i kou manaʻo no ScienceDaily - mahalo mākou i nā ʻōlelo maikaʻi a maikaʻi ʻole. He pilikia paha ka hoʻohana ʻana i ka pūnaewele? Nā nīnau?
Ka manawa hoʻouna: Jul-04-2022